Oxidative stress is essentially an imbalance between the production of free radicals and the ability of the body to counteract or detoxify their harmful effects through neutralization by antioxidants.
Oxidative stress, also known as free radical damage is a core roots and ageing. It affect inside of our body it affects every human being on this planet, mammals included.
What are free radicals?
A free radicals is an oxygen containing molecule that has one or more unpaired electrons, making it highly reactive with other molecules.
Oxygen by-products are relatively unreactive but some of these can undergo metabolism within the biological system to give rise to these highly reactive oxidants. Not all reactive oxygen species are harmful to the body. Some of them are useful in killing invading pathogens or microbes.
However, free radicals can chemically interact with cell components such as DNA, protein or lipid and steal their electrons in order to become stabilized. This, in turn, destabilizes the cell component molecules which then seek and steal an electron from another molecule, therefore triggering a large chain of free radical reactions.
Scientists agree that aging and most deadly diseases are the result of cellular deterioration due to free radicals. Free Radical Damage that causes aging is similar to the same process that causes rust. In a sense, ageing is your body’s way of “rusting” from the inside out.
What are antioxidants?
Every cell that utilizes enzymes and oxygen to perform functions is exposed to oxygen free radical reactions that have the potential to cause serious damage to the cell. Antioxidants are molecules present in cells that prevent these reactions by donating an electron to the free radicals without becoming destabilized themselves. An imbalance between oxidants and antioxidants is the underlying basis of oxidative stress.
Damaged caused by oxidative stress
Oxidative stress has been increasingly recognized as a contributing factor in aging and in various forms of pathophysiology generally associated with aging.
Some of these include neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease, gene mutations and cancers, chronic fatigue syndrome, fragile X syndrome, heart and blood vessel disorders, atherosclerosis, heart failure, heart attack and inflammatory diseases.